Longevity benefits unclear outside deficiency contexts honestly.

IGF-1 elevation raises cancer risk concerns theoretically.

Low physiologic dosing differs from bodybuilding protocols significantly.

Caloric restriction shows stronger longevity data overall.

Improved body composition doesn’t equal extended lifespan.

Excess GH may impair insulin sensitivity longterm.

Deficiency replacement makes sense anti aging claims questionable.

Animal data conflicts with human longevity outcomes.

Higher IGF-1 linked both risks and benefits.

Lifestyle factors likely outweigh exogenous GH impact.